A - Human Necessities – 61 – F
Patent
A - Human Necessities
61
F
A61F 2/02 (2006.01) A61K 35/12 (2006.01)
Patent
CA 2673046
The invention provides a composition including isolated small living tissue particles, a method of making the tissue particles, and a method of using the composition to ameliorate a tissue defect. The tissue particles are composed of cells and their associated extracellular molecules and are sized, in certain embodiments, to be smaller than about 1 mm. Another aspect of the inventive tissue particles is the large percentage of viable cells. In certain embodiments, the tissue particles are made from cartilage and the composition may also contain additives such as adhesives, solutions, and bioactive agents.
L'invention concerne une composition comprenant des particules tissulaires vivantes isolées, un procédé destiné à fabriquer les particules tissulaires et un procédé destiné à utiliser la composition afin d'améliorer un défaut tissulaire. Les particules tissulaires sont composées de cellules et de leurs molécules extracellulaires associées et sont dimensionnées, dans certains modes de réalisation, pour être inférieures à environ 1 mm. Un autre aspect des particules tissulaires de l'invention est le grand pourcentage de cellules viables. Dans certains modes de réalisation, les particules tissulaires sont constituées de cartilage et la composition peut également contenir des additifs tels que des adhésifs, des solutions et des agents bioactifs.
Yao Jian Q.
Zaporojan Victor
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Zimmer Orthobiologics Inc.
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