Method of photochemical immobilization of ligands using...

C - Chemistry – Metallurgy – 07 – K

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C07K 17/06 (2006.01) C07F 7/02 (2006.01) C07H 1/00 (2006.01) C07H 21/00 (2006.01) C07H 23/00 (2006.01) C07J 41/00 (2006.01) C07K 1/04 (2006.01) C07K 17/14 (2006.01) C08J 7/12 (2006.01) C12N 11/06 (2006.01) C12Q 1/00 (2006.01) G01N 33/52 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2217053

There is provided a method of immobilizing a ligand (L) to the surface (P) of a carbon-containing substrate material. The method comprises a photochemical step of linking of one or more photochemically reactive compound (Q) to a carbon-containing material surface (P) wherein the photochemically reactive compound (Q) is a quinone compound containing a cyclic hydrocarbon, or from 2 to 10 fused cyclic hydrocarbons, with at least two conjugated carbonyl groups, and wherein the photochemical step comprises irradiation of the photochemically reactive compound (Q) with non-ionizing electromagnetic radiation having a wavelength in the range from UV to visible light.

L'invention concerne un procédé pour immobiliser un ligand (L) sur la surface (P) d'un substrat contenant du carbone. Ce procédé comprend (a) une étape photochimique de fixation d'un ou de plusieurs composés (Q) à réactivité photochimique sur une surface (P) contenant un matériau carboné. Le composé à réactivité photochimique (Q) est un composé quinone contenant un hydrocarbure cyclique ou 2 à 10 atomes de carbone cycliques fusionnés à au moins deux groupes carbonyle conjugés. L'étape photochimique consiste à exposer le composé (Q) à réactivité photochimique à une radiation électromagnétique non ionisante ayant une longueur d'onde dans la plage allant des UV à la lumière visible.

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