A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 49/00 (2006.01)
Patent
CA 2577312
The present invention generally relates to methods of preselecting patients for treatment with anti-VEGF therapy, anti-HIF therapy or anti-thioredoxin therapy. Aspects of the invention combine methods of dynamic contrast enhanced- MRI and diffusion weighted-MRI for the detection of tumor histology. The methodology disclosed herein detects tissue blood volume, tumor vascularity, and abnormal capillary permeability, thereby determining tumor vascularity to determine whether a patient should be administered such therapy.
La présente invention concerne des méthodes de présélection de patients pour un traitement anti-VEGF, anti-HIF-1 ou anti-thiorédoxine. Des aspects de l'invention combinent des méthodes d'IRM à contraste dynamique et d'IRM pondérée en diffusion pour la détection de l'histologie de la tumeur. La méthode de la présente invention permet de détecter un volume sanguin dans un tissu, une vascularisation tumorale et une perméabilité capillaire anormale et, ainsi, de déterminer si un tel traitement doit être administré à un patient.
Gillies Robert J.
Jordan Benedicte
Kirkpatrick Lynn
Powis Garth
Arizona Board Of Regents On Behalf Of The University Of Arizona
Borden Ladner Gervais Llp
Prolx Pharmaceuticals Corp.
LandOfFree
Method of pre-selecting patients for anti-vegf, anti hif-1... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of pre-selecting patients for anti-vegf, anti hif-1..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of pre-selecting patients for anti-vegf, anti hif-1... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1761945