Method of preparation of insoluble biologically active...

Details Method of preparation of insoluble biologically active... Method of preparation of insoluble biologically active...

C - Chemistry, Metallurgy

12

P

195/123, 167/129

C12P 1/00 (2006.01) C12N 11/08 (2006.01)

Patent

CA 1054081

ABSTRACT OF THE DISCLOSURE This invention relates to a method of preparation of insoluble biologically active insoluble compounds. This method consists in oxidizing a polymer carrier containing a side chain p-phenylenediamine skeleton, which polymer is of the general formula I Image I where R1 is a polymer residue, R2 is a low alkyl group, and x is an integer ranging from 1 to 4, in the presence of a soluble biologically active compound containing a primary amino group selected in the group consisting of enzymes, coenzymes, inhibitors of enzymes, hormones, and antigens. Such insoluble biologically active compounds can particularly be used in affinity chromatography.

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