Method of preparation of pure 4-pyrrolidinophenylbenzyl...

Details Method of preparation of pure 4-pyrrolidinophenylbenzyl... Method of preparation of pure 4-pyrrolidinophenylbenzyl...

C - Chemistry, Metallurgy

07

D

C07D 207/26 (2006.01) A61K 31/402 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2600761

The invention relates to a method for preparing enantiomerically pure 4- pyrrolidinophenylbenzyl ether derivatives of formula I wherein R1, R21, R22, R23, R24 and n are as defined in the description and claims and to intermediates useful in the method of the invention as well as salts thereof.

La présente invention concerne un procédé permettant de préparer des dérivés éther 4-pyrrolidinophénylbenzylique purs sur le plan énantiomérique et répondant à la formule (I), dans laquelle R1, R21, R22, R23, R24 et n sont tels que définis dans la description et les revendications. L'invention concerne également des intermédiaires utiles dans le cadre du procédé de l~invention, ainsi que des sels desdits intermédiaires.

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