Method of preparing 16.alpha.,17.alpha.-dialkylated steroids

C - Chemistry – Metallurgy – 07 – J

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C07J 51/00 (2006.01) C07J 13/00 (2006.01)

Patent

CA 2299396

16.alpha.,17.alpha.-Dialkylated steroids are prepared by reacting a 16.alpha.- alkyl-17(20)-enyl-20-silyl ether with an alkylating agent and an enol silyl ether cleaving agent in a suitable solvent.

Pour préparer des stéroïdes 16.alpha.,17.alpha.-dialkylés, on fait réagir un 16.alpha.-alkyl-17-(20)-ényl-20-silyléther avec un agent alkylant et un agent de clivage de l'énolsilyléther dans un solvant approprié.

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