C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/4375 (2006.01) A61P 35/00 (2006.01) C07D 207/14 (2006.01)
Patent
CA 2748066
Methods of preparing (+)-1, 4-dihydro-7-[(3S,45)-3-methoxy-4-(methylamino)-1 - pyrrolidinyl]-4-oxo-1-(2-thia- zolyl)-1,8-naphthyridine-3-carboxylic acid are disclosed. Also provided are pharmaceutical compositions comprising (+)-1,4-di- hydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2- thiazolyl)-1,8-naphthyridine-3-carboxylic acid, and methods of treatment using such compositions.
Linvention concerne des procédés de préparation dacide (+)-1-dihydro-7-[(3s,4s)-3-méthoxy-4-(méthylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphtyridine-3-carboxylique. Linvention concerne également des compositions pharmaceutiques comprenant de lacide (+)-1,4-dihydro-7-[(3s,4s)-3-méthoxy-4-(méthylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphtyridine-3-carboxylique, et des procédés de traitement utilisant de telles compositions.
Rahuman Mohamed Sheik Mohamed Mujeebur
Subbiah Ramar
Subramani Tamilarasan
Sudhakar Anantha
Osler Hoskin & Harcourt Llp
Sunesis Pharmaceuticals Inc.
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