Method of preparing 2-fluoro-17.beta.-estradiol

C - Chemistry – Metallurgy – 07 – J

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C07J 1/00 (2006.01) C07J 51/00 (2006.01)

Patent

CA 1213881

ABSTRACT 2-Fluoro-17.beta.-estradiol is synthesized by mercurating at C-2 a 17.beta.-estradiol diester or dietherate, displacing the mercury group with fluorine and then re- moving the ester- or ether-protecting groups.

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