Method of preparing 21-alkylated...

Details Method of preparing 21-alkylated... Method of preparing 21-alkylated...

C - Chemistry, Metallurgy

07

J

C07J 13/00 (2006.01) C07J 71/00 (2006.01)

Patent

CA 2238690

Methods for preparing intermediates for 21-alkylated corticosteroids are discloded. Pregna-1,4,16-trien-3,20-diones are contacted with a base and an alkylating agent to produce corresponding 21-alkylated pregna-1,4,16-trien-3,20-diones.

Divulgation de méthodes de préparation d'intermédiaires pour des corticostéroïdes alkylés en 21. On met en contact des prégna-1,4,16-triène-3,20-diones avec une base et un agent d'alkylation pour obtenir les prégna-1,4,16-triène-3,20-diones correspondantes.

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