Method of preparing a separation matrix

B - Operations – Transporting – 01 – J

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B01J 20/30 (2006.01) B01J 20/24 (2006.01) B01J 20/291 (2006.01) C08B 37/12 (2006.01)

Patent

CA 2609093

The present invention relates to a method of preparing an insoluble separation matrix, which method comprises salt-treatment of a polysaccharide gel followed by cross-linking of the polysaccharide polymers. In one embodiment, the method comprises providing an aqueous solution of a gelatable native polysaccharide; lowering the temperature of the polysaccharide solution to a value below its gelling point; salt-treatment by adding at least one salt to the resulting polysaccharide; and cross-linking the salt-treated polysaccharide. The polysaccharide may be prepared e.g. into particles, membranes or monoliths

La présente invention concerne un procédé de fabrication d'une matrice de séparation insoluble, ledit procédé comprenant le traitement en bain de sel d'un gel de polysaccharide, suivi de la réticulation des polymères de polysaccharide. Selon un mode de réalisation, le procédé comprend l'utilisation d'une solution aqueuse d'un polysaccharide naturel gélifiable ; le refroidissement de la solution de polysaccharide jusqu'à une température inférieure à son point de gélification ; le traitement en bain de sel par ajout d'au moins un sel au polysaccharide résultant ; et la réticulation du polysaccharide traité en bain de sel. Le polysaccharide peut être fabriqué sous différentes formes, par exemple sous forme de particules, de membranes, ou de monolithes.

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