Method of preparing biologically active reagents from...

Details Method of preparing biologically active reagents from... Method of preparing biologically active reagents from...

G - Physics

01

N

G01N 33/546 (2006.01) C12Q 1/68 (2006.01) G01N 33/531 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2058515

Biologically active reagents are prepared from particles of copolymers having highly active succinimide groups. The reagents are prepared by having been covalently attached biologically active substances, for example antibodies, to the particles, directly or indirectly through amide groups by displacement of highly active succinimide groups on the particle surface. These reagents are used to advantage in analytical elements, methods for the detection of specific binding ligands (such as immunological species) and immunoassays, and in purification methods such as affinity chromatography.

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