C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
195/131
C12P 13/04 (2006.01) C12P 7/42 (2006.01)
Patent
CA 1239361
ABSTRACT METHOD OF PREPARING D(-)-.beta.- HYDROXYISOBUTYRIC ACID BY FERMENTATION A method is provided for preparing D(-)-.beta.-hydroxyisobutyric acid by fermentation employing isobutyryl chloride or the methyl and/or ethyl esters of isobutyric acid or the methyl and/or ethyl esters of methacrylic acid and/or the acetate and/or formate esters of isobutyl alcohol and/or isobutyl isobutyrate or isobutyl methacrylate as the substrate and a microorganism of the genus Candida and other fungi. In an alternative method, the isolated cells of the various microorganisms are employed with one or mixtures of the above substrates.
470249
Robison Robert S.
Szarka Laszlo J.
Osler Hoskin & Harcourt Llp
Squibb (e.r.) & Sons Inc.
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