Method of preparing highly pure cefpodoxime proxetil

Details Method of preparing highly pure cefpodoxime proxetil Method of preparing highly pure cefpodoxime proxetil

C - Chemistry, Metallurgy

07

D

C07D 501/36 (2006.01) C07D 501/00 (2006.01)

Patent

CA 2389039

Highly pure cefpodoxime proxetil can be prepared by a simple process comprising the step of reacting a cefpodoxime salt with 1- iodoethylisopropylcarbonate in an organic solvent in the presence of a crown ether.

Selon l'invention, du cefpodoxime proxetil à degré de pureté élevé peut être préparé au moyen d'un procédé simple consistant à faire réagir un sel de cefpodoxime avec du 1-iodoéthylisopropylcarbonate dans un solvant organique en présence d'un éther couronne.

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