Method of preparing inhibitors of phosphodiesterase-4

Details Method of preparing inhibitors of phosphodiesterase-4 Method of preparing inhibitors of phosphodiesterase-4

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01)

Patent

CA 2506656

In one aspect, the present invention is directed to a one pot method of preparing intermediates of Formula (V), which are useful in making inhibitors of phosphodiesterase-4. The present invention is also directed to a method of preparing phosphodiesterase inhibitors comprising the Formula (IX, IXa).

Dans l'un de ses aspects, cette invention concerne un procédé de préparation dans un seul pot d'intermédiaires de formule V utiles dans la fabrication d'inhibiteurs de phosphodiestérase-4. Cette invention concerne également un procédé de préparation d'inhibiteurs de phosphodiestérase au moyen des formules (IX) et (IXa).

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