Method of preparing langerhans cell from cd14-positive cell...

Details Method of preparing langerhans cell from cd14-positive cell... Method of preparing langerhans cell from cd14-positive cell...

C - Chemistry, Metallurgy

12

N

C12N 5/0784 (2010.01) A61K 35/14 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) A61P 37/02 (2006.01)

Patent

CA 2533121

A method of preparing Langerhans cells from CD14-positive cells being human peripheral-blood mononuclear cells, comprising culturing human peripheral- blood mononuclear cells in the presence of notch ligand, GM-CSF and TGF-.beta..

L'invention concerne un procédé de préparation de cellules de Langerhans à partir de cellules positives CD14 qui sont des cellules mononucléaires du sang périphérique humain. Ce procédé comporte la culture de cellules mononucléaires du sang périphérique humain en présence d'un ligand Notch, GM-CSF et TGF-.beta..

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