Method of preparing liposomes and products produced thereby

Details Method of preparing liposomes and products produced thereby Method of preparing liposomes and products produced thereby

A - Human Necessities

61

K

167/153, 117/45

A61K 9/50 (2006.01) A61K 9/127 (2006.01)

Patent

CA 1236019

TM-13/14/16 ABSTRACT METHOD OF PREPARING LIPOSOMES AND PRODUCTS PRODUCED THEREBY A method is provided for preparing a stable liposome precursors in the form of a particulate carrier materials coated with thin films of liposome components, which method includes the steps of dissolving at least one liposome-forming amphipathic lipid, optionally, at least one biologically active compound, and, optionally, at least one adjuvant in a suitable solvent and employing the resulting solution to coat a suitable particulate carrier material which is substantially insoluble in the above-mentioned solvent, to form thin films of liposome components thereon. Upon exposing the coated carrier material to water, the thin films of liposome components hydrate. If the carrier material is water-insoluble, it is then separated e.g. by filtrationor centrifuging.

447507

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