Method of preparing optically active cyanohydrins

Details Method of preparing optically active cyanohydrins Method of preparing optically active cyanohydrins

C - Chemistry, Metallurgy

12

P

C12P 17/04 (2006.01) C12P 13/00 (2006.01)

Patent

CA 2084855

The invention relates to a method of preparing an optically active cyanohydrin by addition of hydrogen cyanide to a carbonyl compound, selected from aldehydes and ketones, in the presence of hydroxynitrile lyase, in a biphasic solvent system, comprising a homogeneous aqueous solution of said enzyme, and a suitable organic solvent which is at least substantially immiscible with water. Said method is performed in that said homogeneous aqueous solution is buffered with an acetate buffer having a buffer concentration of between 0.005 and 0.1 mole per litre or with a non-acetate buffer, that the volume ratio organic phase : aqueous phase is between approx. 5:1 and approx. 1:5, and that a solution of hydrogen cyanide and said carbonyl compound in said organic solvent is properly mixed during the reaction period with said homogeneous aqueous solution of hydroxynitrile lyase.

Affiliated with

Also associated with

Rating

Method of preparing optically active cyanohydrins does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of preparing optically active cyanohydrins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of preparing optically active cyanohydrins will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1417949