C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 243/26 (2006.01) C07D 243/24 (2006.01)
Patent
CA 2284961
A method of preparing oxoquazepam which comprises reacting 2,2,2-trifluoroethyltrifluoromethanesulfonate with 7-chloro-1,3-dihydro-5-(2-fluorophenyl)-2H-1,4- benzodiazepin-2-one in tetrahydrofuran or ethyl acetate in the presence of potassium carbonate under reflux. According to the method of the present invention, high purity oxoquazepam can be manufactured in high yields.
Kita Fumio
Ogawa Masaki
Gowling Lafleur Henderson Llp
Ssp Co. Ltd.
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