Method of preparing pharmaceutical dosage forms containing...

A - Human Necessities – 61 – J

Patent

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A61J 3/06 (2006.01) A61J 3/00 (2006.01) A61J 3/10 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2406592

A method for the preparation of pharmaceutical dosage forms comprising multiple powdered active ingredients, in a preferred embodiment, said method comprising the steps of mixing said active ingredients and at least one chosen excipient so as to obtain a powdered mixture; compacting said powdered mixture in a roller-compactor apparatus to obtain a compacted product; breaking and sieving said compacted product to a chosen mesh size to obtain similar sized granules; preferably dry mixing said granules with at least on chosen excipient so as to obtain a granular mixture; forming said granular mixture into unitary dosage forms.

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