Method of preparing vincristine

Details Method of preparing vincristine Method of preparing vincristine

C - Chemistry, Metallurgy

07

D

260/237.3

C07D 519/04 (2006.01)

Patent

CA 1169857

X-5546-(A) Abstract A process for preparing N-formyl vinca dimers, such as vincristine or formyl leurosine which comprises reacting the corresponding dimer in tetrahydrofuran with an aqueous chromate-sulfuric acid solution at a tempera- ture below -50°C.

373921

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