Method of preventing and treating airway remodeling and...

A - Human Necessities – 61 – K

Patent

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A61K 31/522 (2006.01) A61P 11/06 (2006.01)

Patent

CA 2583986

The present invention relates to methods of preventing airway remodeling using A2B adenosine receptor antagonists. This invention finds utility in the treatment and prevention of asthma, COPD, pulmonary fibrosis, emphysema, and other pulmonary diseases. The invention also relates to pharmaceutical compositions for use in the method.

L'invention concerne des procédés de prévention du remodelage des voies aériennes par le biais d'antagonistes du récepteur d'adénosine A2B. Il s'agit d'une invention utile pour le traitement et la prévention de l'asthme, de la bronchopneumopathie obstructive chronique, de la fibrose pulmonaire, de l'emphysème et d'autres maladies pulmonaires. On décrit aussi des compositions pharmaceutiques à utiliser dans le cadre des procédés considérés.

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