Method of preventing and treating hepatic disease using a2b...

Details Method of preventing and treating hepatic disease using a2b... Method of preventing and treating hepatic disease using a2b...

A - Human Necessities

61

K

A61K 31/522 (2006.01) A61P 1/16 (2006.01)

Patent

CA 2646333

The invention is related to methods of preventing and treating hepatic fibrosis using A2B adenosine receptor antagonists and utility in the treatment and prevention of liver damage caused by alcohol abuse, surgical intervention, viral hepatitis, the ingestion of hepatotoxic drugs, or other hepatic diseases. The invention also relates to pharmaceutical compositions for use in the method.

L'invention concerne des procédés permettant de prévenir et de traiter une fibrose hépatique à l'aide d'antagonistes du récepteur de l'adénosine A2B et leur utilité dans le traitement et la prévention de lésions hépatiques provoquées par l'abus de boissons alcoolisées, une intervention chirurgicale, l'hépatite virale, l'ingestion de médicaments hépatotoxiques, ou d'autres maladies hépatiques. L'invention concerne également des compositions pharmaceutiques destinées à être utilisées dans le procédé.

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