Method of preventing inflammatory damage

Details Method of preventing inflammatory damage Method of preventing inflammatory damage

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 39/40 (2006.01) C07K 16/28 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2100084

2100084 9211870 PCTABS00014 A method of inhibiting activated neutrophil-mediated damage to the gut, liver, brain, skin, kidneys, or lungs of a mammal resulting from blood loss followed by transfusion, the method involving administering to the mammal, at the time of or following said transfusion, an organ damage-inhibiting amount of an antibody capable of binding to the CD11b subunit of the neutrophil integrin Mo1, and being substantially incapable of binding to the CD18 subunit of Mo1.

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