Method of preventing surgical adhesions

Details Method of preventing surgical adhesions Method of preventing surgical adhesions

A - Human Necessities

61

K

A61K 35/34 (2006.01) A61K 35/12 (2006.01) A61P 41/00 (2006.01)

Patent

CA 2513640

The present invention relates to a method and composition for preventing surgical adhesions during surgery. Tissue surfaces and/or surgical articles involved in the surgery are separated by a biomaterial provided in the form of a non-crosslinked, decellularized and purified mammalian tissue (e.g. bovine pericardium). The biomaterial effectively inhibits fibrosis, scar formation, and surgical adhesions, while also serving as a scaffold for recellularization of the tissue site.

L'invention concerne un procédé et une composition destinés à la prévention d'adhérences chirurgicales au cours d'opérations chirurgicales. Des surfaces de tissus et/ou des articles chirurgicaux intervenant en chirurgie sont séparés par un biomatériau se présentant sous la forme d'un tissu mammifère non réticulé, décellularisé et purifié (par exemple péricarde du bovin). Le biomatériau inhibe efficacement les fibroses, la formation de cicatrices et les adhérences chirurgicales, tout en servant en même temps de charpente pour la recellularisation du site tissulaire.

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