Method of preventing t cell-mediated responses by the use of...

Details Method of preventing t cell-mediated responses by the use of... Method of preventing t cell-mediated responses by the use of...

A - Human Necessities

61

K

A61K 39/00 (2006.01) A61K 39/02 (2006.01) A61K 39/085 (2006.01) C07K 14/31 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2434119

A method of immunomodulating the T cell response in Staphylococcal bacteria is provided wherein an effective amount of the Map protein from Staphylococcus aureus is administered to a host to prevent or suppress the T cell response. The present method may be utilized with either the Map protein or an effective subdomain of fragment thereof such as the Map10 or Map19 protein. The present invention is advantageous in that suppression or prevention of the T cell response in a host can prevent or ameliorate a wide variety of the pathogenic conditions such as T cell lymphoproliferative disease and toxic shock syndrome wherein the overstimulation of T cell needs to be suppressed or modulated.

L'invention concerne une méthode d'immunomodulation de la réponse des lymphocytes T dans des bactéries staphylococciques, une dose efficace de protéine Map issue de Staphylococcus aureus étant administrée à un hôte en vue de prévenir ou de supprimer la réponse des lymphocytes T. La présente méthode peut être utilisée avec la protéine Map ou avec un sous-domaine efficace d'un fragment de celle-ci, et notamment avec la protéine Map10 ou Map19. L'invention est avantageuse en ce que la suppression ou la prévention de la réponse des lymphocytes T chez un hôte permet de prévenir ou d'améliorer une multitude de pathogénies telles que la maladie lymphoproliférative liée aux lymphocytes T et le syndrome de choc toxique staphylococcique, ces pathogénies nécessitant une suppression ou une modulation de l'hyperstimulation des lymphocytes T.

Affiliated with

Also associated with

Rating

Method of preventing t cell-mediated responses by the use of... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of preventing t cell-mediated responses by the use of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of preventing t cell-mediated responses by the use of... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1776645