Method of producing 5-formyl-2-furylboronic acid

C - Chemistry – Metallurgy – 07 – F

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C07F 5/02 (2006.01)

Patent

CA 2442252

The present invention refers to an improved method of producing 5-formyl-2-furylboronic acid. The method is carried out in a three-step process comprising the steps of: a) addition of a base to a composition comprising a boric acid ester and 2-furaldehyde whereby the formyl functionality of the 2-furaldehyde is protected with a protective group, and b) acidic work-up of the reaction mixture of step a), and c) isolation of 5-formyl-2-furylboronic acid.

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