Method of producing 5'-nucleotide

Details Method of producing 5'-nucleotide Method of producing 5'-nucleotide

C - Chemistry, Metallurgy

07

H

C07H 19/20 (2006.01) C07H 1/02 (2006.01) C07H 19/10 (2006.01) C07H 19/207 (2006.01)

Patent

CA 2100027

A method of producing 5'-nucleotide, which comprises maintaining a nucleoside suspension in an organic solvent at a temperature not lower than about 20°C, and then subjecting the resultant suspension to a phosphorylatipon of the nucleoside(s). According to the present invention, 5'-nucleotide can be produced from a nucleoside at high purity and high yield in a shortened reaction time, and impurity removal in the nucleotide purification process is easily accomplished.

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