Method of producing a thymic microenvironment that supports...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 5/00 (2006.01) A01N 63/00 (2006.01) A01N 65/00 (2006.01) C12N 5/06 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2268284

The present invention relates, in general, to thymic microenvironment and, in particular, to a method of producing a thymic microenvironment. The invention further relates to a method of treating congenital and acquired immunodeficiencies using a thymic microenvironment produced in vitro. Included in acquired immunodeficiencies are syndromes seen in malignant and autoimmune diseases as well as traditional T cell immunodeficiency diseases such as occurs in AIDS.

La présente invention a trait, de manière générale, à un micro-environnement thymique, et, en particulier, à un procédé de production d'un micro-environnement thymique. Cette invention se réfère en outre à une méthode de traitement d'immunodéficiences congénitales et acquises, au moyen d'un micro-environnement thymique produit in vitro. Sont inclus dans les immunodéficiences acquises des syndromes observés dans des affections malignes et des maladies auto-immunes, ainsi que dans des déficits immunitaires classiques des cellules T tels que dans le SIDA.

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