Method of producing amorphous paroxetine hydrochloride

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 405/12 (2006.01)

Patent

CA 2206592

A method of producing amorphous paroxetine hydrochloride, which comprises converting paroxetine or its lower alkanoic acid salt into paroxetine hydrochloride and then spray drying a solution of the hydrochloride.

Méthode pour préparer du chlorhydrate de paroxétine amorphe, consistant à convertir la paroxétine ou son sel d'acide alcanoïque inférieur en chlorhydrate de paroxétine, puis à sécher par pulvérisation une solution du chlorhydrate.

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