Method of producing an antithrombin iii-heparin concentrate...

Details Method of producing an antithrombin iii-heparin concentrate... Method of producing an antithrombin iii-heparin concentrate...

A - Human Necessities

61

K

167/114, 260/116

A61K 35/16 (2006.01) C07K 14/81 (2006.01) C08B 37/10 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1211371

ABSTRACT OF THE DISCLOSURE: In a method of producing an antithrombin III-heparin or an antithrombin III-heparinoid concentrate, heparin or heparinoid is added to human plasma or to anti- thrombin III containing plasma fractions to form an antithrombin III-heparin or antithrombin III-heparinoid complex, the complex thus formed is adsorbed on an anion exchanger, and eluted with a salt solution; then the antithrombin III-heparin or antithrombin III-heparinoid complex contained in the eluate is separated from salts and undesired proteins, and the resulting product is loyphilized.

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