Method of producing chitosan scaffold having high tensile...

Details Method of producing chitosan scaffold having high tensile... Method of producing chitosan scaffold having high tensile...

C - Chemistry, Metallurgy

08

B

C08B 37/08 (2006.01) A61L 15/28 (2006.01) A61L 27/20 (2006.01) A61L 27/56 (2006.01) C08J 9/28 (2006.01) C12N 5/00 (2006.01) C12N 11/10 (2006.01)

Patent

CA 2631345

Provided are a method of producing a porous chitosan scaffold, the method including: providing an aqueous acidic solution having chitosan and a solvent which does not dissolve the chitosan; and freeze-drying the aqueous acidic solution, wherein the solvent is selected from the group consisting of a C3-C8 aliphatic alcohol having one hydroxy group, ethylene glycol monoethylether, ethylene glycol monobutylether, dioxane, tetrahydrofuran, dimethylcarbonate, acetone and acetonitrile, and a chitosan scaffold produced using the method.

L'invention concerne un procédé destiné à produire un échafaudage de chitosane poreux et consistant à obtenir une solution acide aqueuse renfermant un chitosane et un solvant ne dissolvant pas le chitosane, puis à lyophiliser la solution acide aqueuse, le solvant étant choisi dans le groupe constitué par un alcool aliphatique C3-C8 comprenant un groupe hydroxy, de l'éthylène glycol monoéthyléther, de l'éthylène glycol monobutyléther, du dioxane, du tétrahydrofurane, du diméthylcarbonate, de l'acétone et de l'acétonitrile. L'invention concerne également un échafaudage de chitosane produit au moyen de ce procédé.

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