Method of producing coated fine particles

B - Operations – Transporting – 01 – J

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B01J 13/04 (2006.01) A61K 9/10 (2006.01) A61K 9/127 (2006.01) A61K 31/7088 (2006.01) A61K 38/00 (2006.01) A61K 47/24 (2006.01) A61K 47/34 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2596058

A process for producing by a simpler method coated fine particles comprising fine core particles and a coating-layer ingredient with which the core particles are coated. The process is characterized by comprising: a step in which a polar organic solvent in which a coating-layer ingredient is soluble is incorporated into a liquid in such a concentration that fine core particles do not dissolve therein and the coating-layer ingredient can be present therein in a dispersed state, and the fine core particles and the coating- layer ingredient are dispersed in the liquid; and a step in which the fine core particles are coated with the coating-layer ingredient.

L~invention concerne un procédé plus simple de production de particules fines enrobées comprenant des particules fines formant un noyau et un ingrédient formant une couche d~enrobage dont sont enrobées les particules formant un noyau. Le procédé est caractérisé en ce qu~il comprend : une étape dans laquelle un solvant organique polaire, dans lequel est soluble un ingrédient formant une couche d~enrobage, est incorporé dans un liquide en une concentration telle que les particules fines formant un noyau ne s~y dissolvent et que l'ingrédient formant une couche d'enrobage peut être présent à l~état dispersé, et les particules fines formant un noyau et l'ingrédient formant une couche d'enrobage sont dispersés dans le liquide ; et une étape dans laquelle les particules fines formant un noyau sont enrobées par l'ingrédient formant une couche d~enrobage.

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