Method of producing cyclic-aminophenyl ether compound

Details Method of producing cyclic-aminophenyl ether compound Method of producing cyclic-aminophenyl ether compound

C - Chemistry, Metallurgy

07

D

260/293.1, 260/3

C07D 295/08 (2006.01)

Patent

CA 1110246

ABSTRACT OF THE DISCLOSURE Method of producing cyclic-aminophenyl ether compounds or the pharmacologically acceptable salts thereof having the formula: Image wherein R1 represents hydrogen atom or a lower alkyl group, R2 represents a cyclohexyl group which may have been substituted by lower alkyl group(s), an alkyl group containing 1 to 20 carbon atoms, A phenyl group or a benzyl group, R3 represents hydrogen atom, a lower alkyl group, or a cyclohexyl group which may have been substituted by lower alkyl group(s); said R2 and R3 may, however, form together with the adjacent carbon atom a cyclohexane ring which may have been substituted by lower alkyl group(s) and n is 4 or 5. The above compounds have a hypolipemic activity, a cholesterol and a triglyceride reducing activity, and an activity increasing high density lipoprotein (HDL) cholesterol, selectively.

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