Method of producing ketimines

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 249/02 (2006.01) C07C 251/20 (2006.01)

Patent

CA 2346900

The invention relates to a method of producing compounds of formula (1), wherein R1, R2 and R3 are independently hydrogen, halogen, trifluoromethyl or C1-C4 alkoxy, characterized in that a compound of formula (2), wherein R1, R2 and R3 have the meanings defined in formula (1), is reacted with methyl amine in a protic solvent and (b) the obtained compound of formula (1) is purified by recrystallization and /or reaction step (a) is carried out in the presence of a catalyst.

L'invention concerne un procédé pour la production de composés de la formule (1), dans laquelle R¿1?, R¿2? et R¿3? sont indépendamment hydrogène, halogène, trifluorométhyle ou alcoxy C¿1?-C¿4?, caractérisé en ce que (a) un composé de la formule (2), dans laquelle R¿1?, R¿2? et R¿3? ont les significations indiquées dans la formule (1), est mis en réaction avec une méthylamine dans un solvant protique, et (b) le composé obtenu de la formule (1) est purifié par recristallisation et/ou l'étape de réaction (a) est effectuée en présence d'un catalyseur.

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