Method of producing mouse and human endostatin

Details Method of producing mouse and human endostatin Method of producing mouse and human endostatin

C - Chemistry, Metallurgy

07

K

C07K 14/78 (2006.01) C07K 1/113 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2321958

Methods for producing mouse and human endostation are disclosed. Methods for refolding and purifying endostatin from inclusion bodies expressed in bacteria and nucleic acids encoding full-length and truncated forms of endostatin are also disclosed.

L'invention concerne des méthodes de production d'endostatine murine et humaine. L'invention concerne également des méthodes permettant une renaturation et une purification de l'endostatine dans des corps d'inclusion exprimés dans des bactéries et des acides nucléiques codant pour des formes entières et tronquées de l'endostatine.

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