Method of producing oxybutynin and its derivatives

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 229/36 (2006.01) C07C 219/20 (2006.01) C07F 9/655 (2006.01) C07F 9/80 (2006.01)

Patent

CA 2429058

An oxybutynin and its derivatives are produced by reacting a phenyl- ketone with a silylcyanide in the presence of a specified asymmetric catalyst to obtain a siloxynitrile, and then reacting the siloxynitrile with a reducing agent and oxidizing the resulting aldehyde, or subjecting the siloxynitrile to a hydrolysis.

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