C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
195/1.2, 195/1.2
C12N 15/12 (2006.01) C07K 14/01 (2006.01) C07K 14/56 (2006.01) C07K 14/65 (2006.01) C12N 7/01 (2006.01) C12N 7/02 (2006.01) C12N 15/866 (2006.01) C12P 1/00 (2006.01)
Patent
CA 1294231
ABSTRACT OF THE DISCLOSURE Recombinant Bombyx mori nuclear polyhedrosis viruses having, in the polyhedral protein-encoding structural gene portion of the Bombyx mori nuclear polyhedrosis virus DNA (BmNPV DNA), a structural gene for a desired protein as joined to the whole of or a part of the polyhedral protein-encoding structural gene with or without interposition of a linker base sequence, and a method of producing a desired protein which comprises propagating the above recombinant viruses in silkworm- derived cells or silkworms to thereby produce fused proteins of a desired protein and the whole of or a part of the polyhedral protein as joined together with or without interposition of a linking amino acid or peptide and then cleaving the fused proteins at the linking site. to thereby recover a desired protein.
522713
Furusawa Mitsuru
Horiuchi Tadashi
Maeda Susumu
Marumoto Yasumasa
Saeki Yoshiyuki
Daiichi Pharmaceutical Co. Ltd.
Riches Mckenzie & Herbert Llp
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