Method of producing polyunsaturated fatty acids with yeasts...

C - Chemistry – Metallurgy – 12 – P

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C12P 7/64 (2006.01)

Patent

CA 2501264

The invention relates to a method of producing polyunsaturated fatty acids through the incorporation of olefinic or acetylenic fatty acids with a chain length of 13-18 carbon atoms as substrates with a haploid or diploid wild strain of Saccharomyces cerevisiae yeast W 303a or .DELTA.E1o1, which can be used to generate a novel linkage with configuration Z in position 9 of said substrates. The novel desaturation is only produced if the original unsaturation in the administered products has configuration E or is an acetylene. Moreover, if the original linkage has configuration Z, the substrate is recovered unaltered.

L'invention concerne un procédé de production d'acides gras polyinsaturés par incorporation d'acides gras oléfiniques ou acétyléniques de 13-18 atomes de carbone de longueur de chaîne en tant que substrats à une souche haploïde ou diploïde de la levure Saccharomyces cerevisiae W 303a ou ?Elo1, ce qui permet de générer un nouvelle liaison de configuration Z dans la position 9 desdits substrats. La nouvelle désaturation ne se produit que si l'insaturation originale dans les produits administrés présente la configuration E ou est un acétylène tandis que si la liaison originale présente la configuration Z, le substrat est récupéré sans altérations.

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