Method of producing psychotropically and antimicrobially...

Details Method of producing psychotropically and antimicrobially... Method of producing psychotropically and antimicrobially...

C - Chemistry, Metallurgy

07

D

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C07D 409/04 (2006.01) C07C 17/093 (2006.01) C07C 17/14 (2006.01) C07C 57/58 (2006.01) C07D 295/00 (2006.01) C07D 337/14 (2006.01)

Patent

CA 1051896

ABSTRACT OF THE DISCLOSURE : Polysubstituted derivatives of 10-piperazinodibenzo (b,f) thiepin of the general formula (I) : (I) Image wherein R2, R3, R7 and R8 are identical or different and each represents hydrogen, fluorine or chlorine, or a trifluoro- methyl, methoxyl or hydroxyl group, with the proviso that R2 and R3 or R7 and R8 or at least three of the substituents R2, R3, R7 and R8 cannot simultaneously represent hydrogen; R represents an atom of hydrogen, an alkyl or hydroxyalkyl with 1 - 3 carbon atoms, an acyloxyalkyl with 8 - 10 carbon atoms in the acyl and 2 - 3 carbon atoms in the alkyl group, or an ethoxycarbonyl group; and m and n equal 0 or 1; and their addition salts with organic or inorganic acids are psycho- tropically and antimicrobially active compounds. They are useful in psychiatry and neurology.

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