Method of producing solid dosage forms

Details Method of producing solid dosage forms Method of producing solid dosage forms

A - Human Necessities

61

J

A61J 3/10 (2006.01) B30B 11/16 (2006.01)

Patent

CA 2351484

The invention relates to a method of producing solid dosage forms by a) producing a plastic mixture containing at least one active substance and at least one polymer binder, and b) shaping the plastic mixture in a shaping calender with two counter-rotating shaping rollers to give solid dosage forms. Said method is characterized in that one shaping roller has at least one annular groove along its circumference and that the other shaping roller has at least one row of teeth running along its circumference and extending radially outwards, the teeth engaging in the annular groove.

L'invention concerne un procédé de fabrication de moules de dosage compacts, par a) préparation d'un mélange plastique contenant au moins un principe actif et au moins un liant polymère, et b) par moulage dudit mélange plastique pour former les moules de dosage compacts dans une calandre de moulage avec deux rouleaux de moulage tournant en sens inverse. Ce procédé se caractérise en ce qu'un rouleau de moulage comporte au moins une rainure annulaire s'étendant le long de sa périphérie, l'autre rouleau de moulage présentant quant à lui une couronne s'étendant le long de sa périphérie et munie de dents s'étendant vers l'extérieur, qui peuvent entrer dans la rainure annulaire.

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