Method of producing sustained-release preparation

Details Method of producing sustained-release preparation Method of producing sustained-release preparation

A - Human Necessities

61

K

A61K 47/34 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61K 38/19 (2006.01) A61K 38/21 (2006.01)

Patent

CA 2127317

A method of producing a sustained-release preparation which includes permitting a water-soluble polypeptide to permeate into a biodegradable matrix in the aqueous solution. The production method of the present invention makes possible the permeation of a water-soluble polypeptide into a biodegradable matrix without bringing the water-soluble polypeptide into contact with an organic solvent. Hence the water-soluble polypeptide is prepared without affecting the water-soluble polypeptide bioactivity and is thus effective for use as a pharmaceutical.

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