Method of producing sustained-release preparation

Details Method of producing sustained-release preparation Method of producing sustained-release preparation

A - Human Necessities

61

K

A61K 38/00 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61K 9/52 (2006.01) A61K 38/19 (2006.01) A61K 38/22 (2006.01) A61K 38/27 (2006.01) A61K 38/28 (2006.01) A61K 47/30 (2006.01) A61K 47/34 (2006.01)

Patent

CA 2224381

This invention provides a sustained-release preparation comprising a biodegradable polymer metal salt and bioactive polypeptide, with enhanced entrapment of the bioactive polypeptides, a suppression of initial burst, and a constant long-term release of the bioactive polypeptides.

Cette invention concerne une préparation à libération prolongée comprenant un sel métallique de polymère biodégradable et un polypeptide bioactif, avec amélioration de piégeage des polypeptides bioactifs, suppression de la bouffée de départ et libération constante à long terme des polypeptides bioactifs.

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