Method of producing tooth, set of teeth, and method of...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/077 (2010.01) C12N 5/071 (2010.01) A61C 13/00 (2006.01) A61K 6/02 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2610474

A tooth having a specific cell location is obtained by bringing a first cell mass, which substantially comprises one of mesenchymal cells and epithelial cells, into contact with a second cell mass, which substantially comprises the other cells, within a support capable of maintaining these cell masses in the state of being in contact with each other and then culturing them. In a preferred embodiment, the support having individual cell masses therein is further cultured with renal cells , after the completion of the culture.

L~invention permet d~obtenir une dent à lieu cellulaire spécifique en mettant en contact une première masse cellulaire qui comprend substantiellement soit des cellules mésenchymateuses soit des cellules épithéliales, et une deuxième masse cellulaire qui comprend substantiellement d~autres cellules, dans un support capable de maintenir ces masses cellulaires en contact les unes avec les autres et ensuite de les cultiver. Dans une représentation préférée, le support contenant les masses cellulaires individuelles reçoit encore la culture de cellules rénales, une fois la culture achevée.

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