Method of proliferating natural killer cells

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 5/10 (2006.01) C12N 5/071 (2010.01) C12N 5/0783 (2010.01) C12N 5/09 (2010.01) A61P 37/02 (2006.01) C12Q 1/02 (2006.01) A61K 35/12 (2006.01)

Patent

CA 2417579

Anchorage dependent cells for stimulating proliferation which are to be used for proliferating and culturing human natural killer cells in the presence of cells for stimulating the proliferation, characterized by having a detection means introduced thereinto; and a method of proliferating and culturing human natural killer cells by using the above cells. These cells have an effect of stimulating the proliferation of, for example, human natural killer cells and/or precursor cells thereof and are highly sensitive to proliferated and cultured human natural killer cells.

La présente invention concerne des cellules ancrage dépendantes destinées à stimuler la prolifération et qu'on utilise pour faire proliférer et pour cultiver des cellules tueuses naturelles humaines en présence de cellules destinées à stimuler la prolifération, et ces dernières sont caractérisées par le fait qu'un organe de détection y a été introduit. Cette invention concerne aussi une technique de prolifération et de culture de cellules tueuses humaines à l'aide des cellules susmentionnées. Ces cellules ont pour effet de stimuler la prolifération des cellules tueuses naturelles humaines et/ou des cellules précurseur de ces dernières par exemple, et elles sont hautement sensibles aux cellules tueuses naturelles humaines cultivées ou ayant proliféré.

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