Method of promoting bone growth with hyaluronic acid and...

A - Human Necessities – 61 – K

Patent

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A61K 38/18 (2006.01) A61K 9/08 (2006.01) A61K 47/36 (2006.01) A61K 31/725 (1995.01)

Patent

CA 2246747

A bone growth-promoting composition is provided comprising hyaluronic acid and a growth factor. The composition has a viscosity and biodegradability sufficient to persist at the site of desired bone growth for a period of time sufficient to promote the bone growth. Preferably hyaluronic acid is used in a composition range of 0.1-4 % by weight and preferred growth factor is bFGF, present in a concentration range of about 10 -6 to 100 mg/ml.

L'invention concerne une composition favorisant la croissance osseuse, comprenant un acide hyaluronique et un facteur de croissance. Ladite composition présente une viscosité et une biodégradabilité suffisantes pour persister sur le site sur lequel on désire induire la croissance osseuse, pendant suffisamment de temps pour favoriser la croissance osseuse, On utilise de préférence de l'acide hyaluronique dans la composition, à raison de 0,1 à 4 % en poids, et le facteur de croissance préféré est bFGF, en concentration d'environ 10?-6¿ à 100 mg/ml.

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