Method of promoting growth using zinc-containing antibiotic...

A - Human Necessities – 23 – K

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A23K 1/17 (2006.01) A23K 1/175 (2006.01)

Patent

CA 1207582

ABSTRACT A process for obtaining improved growth in food- producing animals such as cattle, sheep and hogs, which comprises administering to said animals the zinc complexes of various monovalent and divalent polyether antibiotics which act as growth promoting agents. Soluble zinc salt is added to a fermentation beer containing the polyether anti- biotics to form an insoluble, recoverable biomass contain- ing the desired zinc antibiotic complexes used in the method of the subject invention. The zinc complexes may be admin- istered as a feed additive, or by subcutaneous implant, preferably on the ear of the animal. The polyether antibiotics which may be used to make the subject zinc complexes include: linear monovalent and divalent polyethers (monensin, nigericin, lasalocid, lyso- cellin, etc.); non-glycolic monovalent monoglycoside poly- ethers (septamycin, dianemycin, lenoremycin, carriomycin and antibiotic A-204); mononitrogen-containing divalent pyrrole ethers (calcimycin, X-14547, etc.); polynitrogen- containing divalent pyrrole ethers (P.-23187, etc.); gly- colic monovalent monoglycoside polyethers (etheromycin, etc.); other polyether antibiotics including ionomycin, aabomycin, disnerycin, duamycin, BL-580, K-41, SF-1195, M-4164A, A-32887, 30,504RP, 38,986, 44,161, 47,433, 47,434 and 47,224. The above zinc complexes are active agents for improving cardiovascular function in animals.

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