Method of promoting neurogenesis

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01) A61P 25/28 (2006.01) C07K 16/18 (2006.01)

Patent

CA 2730073

The present description relates generally to methods of using Abeta binding molecules including, for example, antibodies and antibody fragments that recognize Abeta. The description provides methods of promoting neurogenesis, angiogenesis, synaptic activity and/or dendritic arborization using Abeta binding molecules. The description also provides methods of treating various diseases, disorder, injuries and conditions associated with amyloid plaques or the accumulation of Abeta.

La présente invention concerne de manière générale des procédés d'utilisation de molécules liant Abeta, notamment, par exemple, des anticorps et des fragments d'anticorps qui reconnaissent Abeta. La description concerne des procédés d'activation de la neurogenèse, de l'angiogenèse, de l'activité synaptique et/ou de l'arborisation dendritique employant des molécules liant Abeta. La description concerne également des procédés de traitement de diverses maladies, affections, lésions et états associés aux plaques amyloïdes ou l'accumulation d'Abeta.

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