Method of prophylaxis or treatment of antigen presenting...

Details Method of prophylaxis or treatment of antigen presenting... Method of prophylaxis or treatment of antigen presenting...

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 38/17 (2006.01) A61P 17/00 (2006.01) C12P 21/08 (2006.01)

Patent

CA 2120732

Methods of using inhibitors of the CD2/LFA-3 interaction in treating skin conditions characterized by increased T cell activation and abnormal antigen presentation in the dermis and epidermis in mammals, including humans. Sugh conditions include psoriasis, UV damage, atopic dermatitis, cutaneous T cell lymphoma such as mycosis fungoides, allergic and irritant contact dermatitis, lichen planus, alopecia areata, pyoderma gangrenosum, vitiligo, ocular cicatricial pemphigoid, and urticaria.

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