A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61K 39/085 (2006.01) A61K 39/385 (2006.01) A61P 31/04 (2006.01) A61P 37/04 (2006.01) C07K 16/12 (2006.01) C12N 1/20 (2006.01)
Patent
CA 2658508
A method of preventing or treating staphylococcal bacterial infection in an individual is disclosed. A vaccine based on a conjugate of PS1 polysaccharide antigen can be used for active protection in individuals who are to be subjected to conditions that place them at immediate risk of developing a bacterial infection, as would be case in the context of a catheterization or a surgical procedure. Alternatively, antibodies raised in response to the antigen can be used to treat or to provide passive protection to individuals. The method can be used in a population of patients at risk for infection by various species of Staphylococcus or various types of Staphylococcus epidermidis.
L'invention concerne un procédé de prévention ou de traitement d'une infection bactérienne à staphylocoque. Un vaccin à base de conjugué d'antigène de polysaccharide PS1 peut être utilisé pour fournir une protection active à des sujet soumis à des conditions constituant un risque immédiat d'infection bactérienne, cathétérisation ou processus chirurgical. En variante, une haute concentration d'anticorps générés en réponse à l'antigène peut être utilisée pour traiter ou protéger passivement des sujets. Le procédé peut être utilisé sur une population de patients risquant d'être infectés par diverses espèces de staphylocoque ou divers types de staphylococcus epidermidis.
Ennifar Sofiane
Fattom Ali
Kossaczka Zuzana
Sarwar Jawad
Taylor Kimberly L.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Glaxosmithkline Biologicals Sa
Nabi Biopharmaceuticals
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