Method of purifying macrolides

Details Method of purifying macrolides Method of purifying macrolides

C - Chemistry, Metallurgy

07

G

C07G 3/00 (2006.01) C07D 498/18 (2006.01) C07G 5/00 (2006.01)

Patent

CA 2533548

Provided is a method of purifying a macrolide, especially tacrolimus, that includes loading macrolide onto a bed of sorption resin and elting with a suitable eluent such as a combination of water and tetrahydrofuran.

L'invention concerne un procédé de purification d'un macrolide, en particulier le tacrolimus, qui consiste à charger le macrolide sur un lit de sorption et à procéder à son élution au moyen d'un éluant approprié de type combinaison d'eau et de tétrahydrofurane.

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